Higher spermidine intake linked to cognitive performance

New research shows that diets high in spermidine may enhance cognitive abilities in older adults, particularly men and those with chronic health issues.

Higher spermidine intake linked to better cognitive performance in older adults

Recent research has found a connection between higher dietary intake of spermidine and improved cognitive performance among older adults. This study noted that the effect was especially strong in men, people with elevated body mass, and those living with certain chronic health conditions like hypertension. Published in the Journal of Affective Disorders, the analysis used data from the U.S. National Health and Nutrition Examination Survey collected from 2011 to 2014, examining the dietary habits and cognitive test results of 2,674 participants aged 60 and older. Those consuming higher amounts of spermidine performed noticeably better on cognitive assessments, with the strongest results among males and non-Hispanic Whites. Foods high in spermidine include mushrooms, whole grains, and aged cheese, but the compound is also available as a dietary supplement.

This study opens a new chapter in understanding the potential benefits of dietary spermidine for cognitive health in older adults. Its focus on specific demographic groups shows that certain populations may derive even more benefit from increased spermidine intake. However, while the association is compelling, the lack of causal evidence implies a need for further research. Factors like diet or lifestyle choices could also influence cognitive health, complicating the findings. It highlights an intriguing pathway for nutritional strategies aimed at aging populations, emphasizing the importance of diet in maintaining cognitive abilities as we age.

Highlights

This research highlights the promising role of nutrition in enhancing cognitive health in older age.