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Gabapentin linked to dementia risk

New research shows frequent use of gabapentin may raise dementia risk by up to 40%.

July 19, 2025 at 01:51 AM
blur Explained: Gabapentin’s hidden side effects-From pain relief to brain fog

Gabapentin, a common painkiller, shows a potential link to higher dementia risk in frequent users.

Gabapentin linked to increased dementia risk

A new study reveals that long-term use of gabapentin, a medication commonly prescribed for nerve pain, may significantly increase the risk of dementia. The research examined the medical records of patients from 68 U.S. health systems, finding that those who received six or more prescriptions of gabapentin were 29% more likely to develop dementia compared to those with fewer prescriptions. For patients receiving 12 or more prescriptions, the dementia risk soared to 40%. Younger users, particularly those aged 35 to 49, demonstrated even higher risks, making this a significant health concern.

Key Takeaways

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Gabapentin may increase dementia risk by 29-40% in frequent users.
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Younger users, especially those aged 35-49, are more affected.
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The correlation does not prove causation but warrants caution.
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Patients should discuss long-term use with their doctors.
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Alternative pain management options may exist.
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Lifestyle changes can support brain health and cognition.

"Patients who received six or more prescriptions were 29% more likely to develop dementia."

This statistic underscores the growing concern regarding gabapentin and cognitive health.

"This is a wake-up call: time to talk to your doctor, think critically, and monitor brain health."

An essential reminder for patients to stay informed about their medication's risks.

This study highlights a troubling trend in prescribing practices for chronic pain management. As gabapentin has been marketed as a safer alternative to opioids, the new evidence suggests that it requires careful re-evaluation. While the findings do not definitively prove that gabapentin causes dementia, they raise awareness about the importance of monitoring long-term medication use, especially in younger patients. Doctors and patients should engage in open conversations about risks, alternative treatments, and lifestyle choices that can help support cognitive health.

Highlights

  • Gabapentin use could heighten dementia risk significantly.
  • Younger patients may face even greater risks with gabapentin.
  • This medication is not as safe as once thought.
  • Time to rethink long-term gabapentin prescriptions.

Potential risks with gabapentin prescriptions

Frequent use of gabapentin may lead to increased risk of dementia, particularly in younger patients. This raises concerns about the long-term effects of a commonly prescribed medication.

Ongoing discussions and research around gabapentin and its effects are crucial as more studies emerge.

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