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Benadryl linked to possible dementia risk
Doctors warn about the potential danger of using Benadryl regularly.

Doctors are raising concerns over Benadryl and a potential link between the common over-the-counter allergy medication and a brain disease.
Concerns rise over Benadryl and dementia risk
Doctors have found a potential link between Benadryl, a common allergy medication, and an increased risk of dementia. Millions of Americans use Benadryl every year for allergy relief, but recent studies suggest that its active ingredient, diphenhydramine, may cross the blood-brain barrier. This can block a crucial neurotransmitter called acetylcholine, essential for memory and learning. Research indicates that regular use of Benadryl raises the risk of dementia by 54 percent and Alzheimer's by 63 percent. Doctors emphasize that while occasional use might be safe, frequent consumption could be concerning. They urge users to consider alternatives like newer antihistamines.
Key Takeaways
"There have been several studies that show an association between Benadryl and dementia, particularly in older patients."
Dr Joao Lopes emphasizes serious concerns over Benadryl's link to dementia in older patients.
"Occasional use [of Benadryl] is fine and nobody needs to run home and throw out their stash."
Dr Anna Wolfson reassures that not all use of Benadryl is dangerous, but encourages caution.
"We believe that diphenhydramine has reached the end of its life cycle... it is a relatively greater public health hazard."
A paper from medical experts strongly advises against the continued use of diphenhydramine due to risks.
The growing concerns over Benadryl illustrate the delicate balance between public health and individual choice. While it has been a go-to for allergy relief for decades, the increasing evidence linking it to severe cognitive risks raises questions about its continued availability and promotion. The medical community is shifting towards advising safer alternatives, highlighting a trend away from older medications that may no longer be suitable in today's context. This serves as a reminder of the importance of ongoing evaluations of long-standing treatments in light of new research.
Highlights
- Benadryl raises new questions about safety in the elderly.
- Occasional use of Benadryl may be safe, but caution is advised.
- Doctors fear the long-term impact of Benadryl on brain health.
- The medical community is shifting away from older allergy treatments.
Potential health risks associated with Benadryl
Ongoing evidence suggests a concerning link between Benadryl and dementia, prompting doctors to recommend caution for frequent users.
Future discussions around Benadryl may focus on the need for safer alternatives.
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