Woman discovers rare sperm allergy affecting fertility

A woman in Lithuania discovers an allergy to her partner's semen is impacting her ability to conceive.

Rare condition affects woman's fertility struggle

A 29-year-old woman from Lithuania, who faced challenges in conceiving with her partner, learned she has a rare sperm allergy. Despite undergoing two rounds of IVF without success, doctors could not initially identify any reasons for her infertility. After considering her history of asthma and various allergies, she underwent tests that revealed sensitivity to Can f 5, which is linked to male dog allergens and human semen. This condition, known as seminal plasma hypersensitivity, affects fewer than 100 people worldwide. Symptoms include nasal congestion and skin irritation, and while it does not directly cause infertility, it complicates conception. Although options like antihistamines and intrauterine insemination exist to manage her allergy, treatment was limited in her area. After trying antihistamines without success, the couple faced continued difficulties.

The case of this woman sheds light on a rarely discussed medical issue that may be more widespread than acknowledged. Seminal plasma hypersensitivity could explain unexplained infertility in many couples, who are often led to believe their challenges result from more common factors. As awareness grows, medical professionals may need to adjust how they approach fertility evaluations, particularly in patients who report symptoms that resemble other conditions. Lack of understanding and misdiagnosis can delay appropriate treatments, a disheartening reality for couples eager to start families. Research into this condition might prompt better recognition and therapeutic developments, helping those affected to navigate their fertility journeys more effectively.

Highlights

As medical knowledge expands, it is crucial for more individuals to understand this rare yet impactful allergy.