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Study reveals gender gap in MS treatments

New research shows women aged 18-40 are less likely to receive disease-modifying therapies than men.

August 5, 2025 at 07:30 PM
blur Sex-related gap found for use of DMTs in MS patients ages 18-40

A new study reveals that women with multiple sclerosis are less likely to receive critical therapies than men.

Significant gender disparity found in disease-modifying therapies for MS

A recent study from France indicates that women aged 18 to 40 with multiple sclerosis are significantly less likely than their male counterparts to receive disease-modifying therapies (DMTs). This research, focusing on patients diagnosed with relapsing-remitting MS, highlights a persistent ‘sex-related gap’ in access to effective treatments. The study analyzed health records of over 22,000 patients, revealing that only 60.2% of women received DMTs over the observed period compared to 61.3% for men, with women being 20% less likely to receive highly effective therapies. Experts stress the importance of educating both clinicians and patients on the safe use of these therapies, especially in relation to pregnancy, as this disparity could lead to worse long-term outcomes for women.

Key Takeaways

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Women with MS are less likely to receive DMTs than men of the same age.
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The percentage of MS patients receiving highly effective DMTs is lower for women.
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Awareness of DMT safety during pregnancy is lacking among patients and doctors.
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Inertia in treatment decisions can have harmful consequences for women with MS.
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Women’s treatment often declines in anticipation of pregnancy, affecting long-term health.
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Education on DMT guidelines is crucial to close the sex-related gap in treatment.

"This loss of chance is not acceptable anymore as there are drugs that are compatible with pregnancy."

Sandra Vukusic emphasizes the need for equitable access to treatment for women during childbearing years, stressing the role of DMTs in managing MS effectively.

"We found that women were less likely to be treated with a disease-modifying drug than men with the same level of disease severity."

Sandra Vukusic outlines the study's core discovery regarding treatment differences between genders in MS care.

The findings underline a glaring gap in the treatment of multiple sclerosis, particularly for women. Given that women are generally at higher risk for MS and usually face unique challenges regarding treatment during their childbearing years, the need for awareness and education cannot be overstated. Sandra Vukusic, one of the study's authors, stresses that withholding effective therapies undermines women's health. As treatment protocols evolve, understanding the implications of these therapies in pregnancy becomes essential. A proactive approach is required to eliminate this disparity and ensure that all patients benefit equally from the advances in MS treatments.

Highlights

  • Women deserve equal access to effective MS treatments.
  • A significant gender gap impacts MS treatment options.
  • Understanding DMTs during pregnancy is vital for women's health.
  • Delaying treatment can worsen outcomes for women with MS.

Concerns over treatment inequality for MS

The disparity in accessing disease-modifying therapies raises serious implications for women's long-term health outcomes. Ensuring equity in treatment options is critical to preventing disability.

Addressing this disparity in treatment is essential for the future health of women with MS.

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