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Early signs of multiple sclerosis identified in new research

A study from the University of Columbia reveals warning signs of MS can appear years before diagnosis.

August 5, 2025 at 06:00 AM
blur Researchers pinpoint key warning signs of MS that are routinely ignored... would YOU recognise them?

Researchers at the University of Columbia have identified subtle symptoms that precede multiple sclerosis.

New study uncovers early warning signs of multiple sclerosis that are often overlooked

A recent study conducted by researchers at the University of Columbia highlights fatigue, anxiety, and pain as key yet often ignored signs of multiple sclerosis (MS). The study examined health records from 12,000 individuals and traced physician visits over the prior 25 years, revealing that these symptoms could emerge as much as 15 years before well-known MS signs like walking difficulties and vision problems. Notably, there was an increase in general physician visits for these early symptoms a decade and a half in advance. The findings suggest that patterns of healthcare usage may indicate MS's onset, enabling potential early interventions.

Key Takeaways

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Fatigue, anxiety, and pain can be early signs of MS, appearing 15 years prior to diagnosis.
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Healthcare visits for these signs increased well before major symptoms arise.
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Most people are diagnosed with MS in their thirties or forties, despite signs starting much earlier.
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The findings underline the importance of early detection and intervention.
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Factors like vitamin D deficiency and stress may contribute to the rising MS cases.
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There is currently no cure for MS, but treatments can slow disease progression.

"Signs can be easily mistaken for other conditions"

Dr. Helen Tremlett highlights the challenge in recognizing early MS symptoms.

"These findings dramatically shift the timeline for when early warning signs begin"

Dr. Marta Ruiz-Algueró emphasizes the new understanding of MS symptoms.

This new research shifts the understanding of when multiple sclerosis might present itself. Traditionally, medical professionals focused on symptoms that typically appear five years before the diagnosis. However, the study reveals that fatigue and mental health issues arise significantly earlier. This could lead to key changes in diagnosing and managing MS, allowing for timely treatment interventions. With cases reportedly rising, understanding these early signs is crucial and may ultimately change the landscape of MS healthcare.

Highlights

  • Fatigue and pain are red flags for MS that many overlook.
  • Identifying early signs can change the game for MS treatment.
  • Understanding MS means spotting the signs far before diagnosis.
  • This research could improve early detection of multiple sclerosis.

Concerns over rising MS cases and public awareness

The increase in diagnosed multiple sclerosis cases raises concerns about healthcare systems and public health strategies. Early diagnosis could reduce long-term health costs and improve patient outcomes.

Addressing these early signs could pave the way for improved outcomes for MS patients.

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