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New diabetes variant discovery could alter treatment

Researchers identify a third type of diabetes affecting 2 million Americans, highlighting genetic factors.

July 22, 2025 at 07:35 PM
blur Scientists discover new form of condition suffered by 38million Americans... putting even more at risk

A team of researchers has identified a potential new type of diabetes that could affect millions.

New diabetes variant discovered that may impact millions

Researchers from the UK and US have identified a new variant of diabetes, which may affect approximately 2 million Americans with type 1 diabetes. This discovery suggests that about 66 percent of patients diagnosed with the disease may not have the characteristic immune response typical of type 1 diabetes. The study conducted on individuals of sub-Saharan African descent revealed that many of them do not possess the antibodies that indicate the autoimmune nature of type 1 diabetes. This finding could lead to new treatment strategies for improving health outcomes in affected individuals, who face a higher risk of premature death compared to their peers.

Key Takeaways

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Potential new diabetes variant identified
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Approximately 2 million Americans may be affected
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66 percent of patients lacked typical type 1 diabetes antibodies
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New understanding challenges autoimmune definitions
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Study highlights health disparities in diabetes care
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Tailored treatments may improve outcomes for diverse populations

"The identification of this type 1 diabetes in sub-Saharan African populations suggests a potential ancestral or genetic link."

Dr. Dana Dabelea emphasizes the significance of potentially genetic factors in type 1 diabetes.

"These findings support the common existence of a non-autoimmune insulin-deficient subtype of diabetes."

The research team discusses the implications of their findings for understanding diabetes subtypes.

The emergence of this new diabetes variant opens doors to understanding health disparities in diabetes care, especially among marginalized populations. With type 1 diabetes historically characterized as an autoimmune disorder, this new understanding challenges existing definitions. Researchers emphasize the need for tailored treatment approaches for diverse populations, underscoring the importance of genetic factors in developing diabetes. Considering the significant number of cases anticipated globally, this discovery could fundamentally change diabetes management and prevention strategies in the future.

Highlights

  • New understanding of diabetes could reshape treatment pathways.
  • This discovery highlights a pressing need for tailored healthcare solutions.
  • Millions may benefit from this breakthrough in diabetes research.
  • Diversity in diabetes presents a challenge and an opportunity.

Potential risk of misdiagnosis and treatment delays

As this new diabetes variant may not present with typical antibody features, there is a risk of misdiagnosis. This could lead to delays in appropriate treatment, potentially worsening health outcomes for patients.

Ongoing research is essential to unravel the complexities of this newly discovered diabetes variant.

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