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Natural pain relief explored by experts

A new look at how the body fights pain and the growing toolbox beyond pills. Learn how to use movement, mind and medicine wisely.

August 26, 2025 at 10:00 AM
blur Pain relief comes from more than meds. Dr. Sanjay Gupta explains your body’s natural painkillers

A look at how the body can provide natural pain relief and what new science says about managing pain beyond medications.

Pain relief comes from within

Dr. Gupta argues that pain relief is more than pills. The piece explains the body’s internal pain control system, including endorphins and the endogenous opioid network, and it notes how mood and social support can change pain perception. It positions relief as an inside job and highlights how everyday moments of comfort and connection can translate into physical ease.

Beyond NSAIDs and acetaminophen, the article reviews risks from long term NSAID use and revisits aspirin for primary heart prevention. It also discusses supplements and the need for medical guidance, while pointing to new non opioid medicines that target specific pain pathways. The piece traces how clinics are expanding tools to include nerve blocks, ketamine and other approaches, signaling a shift away from opioids in some settings.

The narrative ends with a reminder that pain relief is a moving field. It shows doctors balancing traditional remedies with evolving science, and it invites readers to view pain management as a blend of evidence, personal daily practices, and ongoing medical guidance.

Key Takeaways

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Pain relief can come from internal body systems like endorphins and the endogenous opioid network
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Placebo effects influence pain by shaping expectations and brain chemistry
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MEAT offers a movement and activity based approach to injury recovery
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NSAIDs carry important short term and long term risks and should be used with caution
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Aspirin guidelines for primary prevention are evolving for some age groups
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New non opioid drugs target specific pain pathways and may reduce reliance on opioids
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Supplements vary in evidence and safety and require medical guidance
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ER and clinic practices are expanding to non opioid strategies like nerve blocks and ketamine

"When you look at the release of norepinephrine and opioids for the fight or flight response it is one of the most potent analgesic molecules"

Explanatory quote about natural pain control during stress

"Endogenous opioids have an insider advantage as a natural part of the body’s interwoven system for pain modulation"

Describing the internal pain relief system

"Placebo is a legitimate tool in your pain toolbox"

Noting the value of the placebo effect

The article blends reporting with a cautious editorial voice. It invites readers to rethink quick fixes and shows how science is expanding a toolbox beyond meds. It also signals that pain management is personal and context dependent, not a one size fits all solution.

It raises questions about access, cost and how new therapies will be evaluated for safety and value. It also stresses the need for careful interpretation of supplements and home remedies and the importance of professional medical advice to navigate risks and benefits.

Highlights

  • Pain relief starts inside the body
  • Move and breathe your pain away before you reach for a pill
  • Our bodies carry a built in toolkit for healing
  • Placebo effects are real tools in the pain toolbox

Public health and drug safety concerns

The article touches on aspirin guidelines, NSAID risks, supplements, and new non opioid therapies. These topics have public health implications and potential for misinterpretation, so clear medical guidance is important.

Healing is a journey that blends science with daily habits.

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