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Antidepressant withdrawal gaps
A new report shows many patients struggle to taper off antidepressants despite guidance.

A long running struggle to help patients taper off antidepressants reveals gaps in support and policy.
British health system confronts antidepressant withdrawal gaps
Helena Burton, a 56 year old psychotherapist from Essex, stopped venlafaxine after 15 years and faced numbness, brain zaps and a sense of unreality. Medical staff dismissed withdrawal claims and suggested relapse instead. In 2019 leading medical bodies shifted stance after mounting evidence, and guidelines now encourage slow tapering to reduce withdrawal risks. Yet dosing challenges persist because venlafaxine is only available in coated form, making precise reductions hard without tools or liquid versions. Helena finally found relief through hyperbolic tapering and long term support, but her path was costly and time consuming.
The broader system shows similar gaps. NHS guidance recommends tapering for other hard to quit medicines such as steroids and beta blockers, but real world support remains patchy. A 2019 public health push for a helpline and online resources never fully materialized. A 2023 update from NICE emphasizes staged dose reductions, yet clinicians often lack training in deprescribing. A recent JAMA Psychiatry study questioned withdrawal concerns, while proponents argue that long term use increases risk and severity of withdrawal. Across the care spectrum patients describe how difficult it is to taper without accessible formulations, timely guidance, or dedicated clinics. A US network called Outro offers guided tapering for a fee and shows a model that UK clinics hope to adopt. Meanwhile some patients like Kiera Dawes recount painful experiences with other medicines and note that withdrawal relief requires real support from pharmacists and GPs.
Key Takeaways
"Coming off the prescribed antidepressant after taking it for 15 years felt like there was a bomb going off in my head"
Helena Burton describes her withdrawal experience
"Withdrawal effects will be much more severe when people have been on the drugs for years"
Joanna Moncrieff on long term use and withdrawal
"Most NHS clinicians are not educated in how to get people off drugs. That leads to a lot of harm"
Dr Mark Horowitz on deprescribing gaps
"Withdrawal symptoms are often only in patients imaginations"
A JAMA Psychiatry paper cited in the article
The withdrawal story is a test of a health system. For decades doctors and drug makers resisted patient reports, then policy shifted without parallel funding or clear implementation paths. The result is a mismatch between guidance and practice, leaving many patients to navigate complex dosage changes on their own. A stronger deprescribing culture would require training for clinicians, better dosing options, and formal pathways that connect patients to supervised tapering. The pace of reform matters: without timely access to tailored taper plans and affordable formulations, the human cost compounds already existing health problems.
Looking ahead, the key question is not just whether guidelines exist but whether the system will fund and staff real tapering programs. A public health shift that treats deprescribing as essential care could reduce harm, improve trust, and cut long term drug dependence. If NHS leaders act, patients will hear that stopping the wrong way can become stopping safely rather than a breach of care.
Highlights
- Tapering is essential for safe withdrawal
- Withdrawal is real and often longer than people expect
- Doctors must be trained to deprescribe safely
- No one should suffer withdrawal in silence
Policy and budget risks around deprescribing
The piece highlights gaps between guidelines and real world support for stopping antidepressants. Budget constraints and political attention could slow the creation of NHS deprescribing clinics and helplines, risking ongoing patient harm and public backlash.
Change will require action, funding, and a commitment to patients beyond books and guidelines.
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